The information provided here is meant to give you a general idea about each of the medications listed below. Only the most general side effects are included, so ask your healthcare provider if you need to take any special precautions. Use each of these medications as recommended by your healthcare provider, or according to the instructions provided. If you have further questions about usage or side effects, contact your healthcare provider.

Medications may help to either prevent or reduce side effects of treatment, or to manage certain side effects once they occur. Since you can develop these symptoms from the treatment and/or from the cancer itself, it is essential that you discuss them with your doctor when you notice them and ask him or her if any of these medications are appropriate for you.

Bisphosphonates

Common names include:

  • Pamidronate (Aredia)
  • Clodronate (Bonefos or Ostac)

Multiple myeloma often damages the bones. Bisphosphonates are used to help prevent bone pain and fractures by helping the body restore and repair bone that has been damaged by the growth of myeloma cells. Bisphosphonates include the following:

Pamidronate is given as a monthly injection. Clodronate is given daily by mouth. These drugs are used in addition to chemotherapy . Studies show they decrease the risk of bone pain and fractures by blocking the further breakdown of bone. The most frequently noted side effect is a fever.