THURSDAY, April 17 (HealthDay News) -- Women who have weekly
migraines are at an increased risk for stroke compared to those
with few or no migraines, a new study finds.
On the other hand, those with less frequent migraines may have
an increased risk of heart attack, the same team of researchers
report.
The findings, to be presented Thursday at the American Academy
of Neurology annual meeting in Chicago, point to different
mechanisms linking migraines to distinct cardiovascular troubles,
experts say.
And even though the average migraine sufferer's absolute risk of
a heart attack or stroke is still low, the new study should be
viewed in the context of other cardiac risk factors, said Dr.
Richard Lipton, vice chairman of neurology at Montefiore Headache
Center in New York City.
"Someone with migraine should be sure to manage their other risk
factors including high blood pressure, diabetes, smoking, high
cholesterol and body weight," said Lipton. He was not involved in
the study, which was conducted by a team from Brigham & Women's
Hospital and Harvard Medical School in Boston.
Previous research (much of it by the same group) has found an
increased risk of vascular problems in both men and women who
experience migraines, especially those who experience migraine with
visual symptoms known as aura.
One recent study found that women who suffer from migraines with
aura are at higher risk of stroke, especially if they smoke and
take oral contraceptives.
What's been missing, however, is data on how the frequency of
migraines might affect cardiovascular risk.
This study involved almost 28,000 female health professionals in
the United States aged 45 and older, none of whom had
cardiovascular disease when the trial started.
During about 12 years of follow-up, and compared to women with
no migraines, women with less-than-monthly migraines turned out to
be 54 percent more likely to develop cardiovascular disease. Those
with weekly migraines were almost twice as likely to develop heart
troubles.
Those with fewer-than-monthly migraines had a 45 percent
increased risk of having an ischemic stroke (one resulting from
constricted blood flow) and a 64 percent increased risk for heart
attack, compared to women with no migraines, the Boston team
found.
Women who suffered migraines at least weekly had a 49 percent
increased risk for heart attack and almost triple the increased
risk for stroke, they added.
According to Lipton, repeat migraine attacks may have a direct
influence on the risk of stroke. "This is plausible because, during
the aura, there are profound changes in the brain which diminish
blood flow to the brain," he explained. "Stroke is usually caused
by diminished blood flow to the brain."
If this were true, preventing migraines should decrease the risk
of stroke, although this hypothesis has not yet been tested.
It's also possible that frequent migraines simply point to an
increased risk for stroke, rather than actually causing it, Lipton
said.
Either way, there's no reason to panic.
"Even if the relative risk of stroke triples in those with
frequent migraine, the absolute risk for most people remains low,"
Lipton said. "If someone who would otherwise have a stroke risk of
20 per 100,000 has that risk triple due to frequent migraine -- to
60/100,000 -- they are [still] very unlikely to have a stroke."
More information
Find out more about migraines at
The National
Migraine Association.