THURSDAY, April 17 (HealthDay News) -- Without using an egg,
researchers have been able to reprogram certain mature cells back
to an embryonic-stem-cell-like state, a new report says.
A research team from Massachusetts Institute of Technology
performed the feat on mature B cells, immune cells that can bind to
specific antigens, such as proteins from bacteria, viruses or
microorganisms. They said their finding, confirmed when they were
able to develop mice from the reprogrammed cells, may help enable
the creation of models that will lead to a better study and
understanding of autoimmune diseases such as multiple sclerosis and
type 1 diabetes.
"In principle, this will allow you to transfer a complex genetic
human disease into a Petri dish, and study it. That could be the
first step to analyze the disease and to define a therapy," Rudolf
Jaenisch, an MIT professor of biology, said in a prepared
statement.
The findings are published in the April 18 issue of
Cell.
More information
The U.S. National Institutes of Health has more about
stem
cells.
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