TUESDAY, April 15 (HealthDay News) -- The stress of being
diagnosed with breast cancer -- not the chemotherapy treatment to
combat it -- may be responsible for patient complaints about
problems with memory and concentration, two new studies
suggest.
"This is an important issue, particularly as survival rates for
breast cancer improve," study author Dr. David G. Darby, chief
medical officer of CogState Ltd., the Australian company that
developed the cognitive tests used in the studies, said in a
prepared statement. "People could be making decisions about whether
or not to have chemotherapy based on stories they've heard about
'chemofog' or 'chemobrain.' Hopefully, this information will help
people make informed decisions."
The studies were to be presented April 15 at the American
Academy of Neurology annual meeting, in Chicago.
In the first study, cognitive tests were given to 30 women with
breast cancer before each cycle of chemotherapy and also to 30
healthy women. The breast cancer patients had slight problems in
attention and learning skills before chemotherapy even started.
After treatments, they showed a minor slowing in thinking speed.
Three women, or 10 percent, did develop cognitive problems during
chemotherapy.
"We also found that the women who reported that they had
problems with memory, concentration and other cognitive skills were
not actually the ones who developed problems as determined by the
tests," Darby said.
The second study tested the cognitive abilities of three groups
of women -- pre-treatment breast cancer patients, recent
post-benign biopsy patients and breast cancer survivors who were
one year past completed treatment. They were also evaluated for
anxiety, depression, their overall quality of life and the amount
of social support they had.
The recently diagnosed women and those who recently had benign
biopsies scored about the same on tests of working memory and
spatial learning. However, both groups were slower and less
accurate than the breast cancer survivors. In addition, memory and
learning scores for the breast cancer patients did not dip
significantly during the initial stages of treatment, the study
found.
The recently diagnosed women who had better overall quality of
life also had better scores on the cognitive tests.
"These results suggest that cognitive difficulties experienced
by women with a new breast cancer diagnosis may be related to
stress as a result of the diagnosis and other quality-of-life
factors, and not simply due to the effects of chemotherapy or
radiation," study author Michael J. Boivin, of Michigan State
University, said in a prepared statement.
More information
The U.S. National Cancer Institute has more about
breast cancer.