MONDAY, April 7 (HealthDay News) -- A fast method to detect fake
Tamiflu, the mainstay medication for preventing and treating bird
flu, has been developed to stop counterfeiters trying to make money
off the demand for antivirals that fight the deadly disease.
Chemists in Georgia are scheduled to describe how Desorption
Electrospray Ionization Mass Spectrometry (DESI-MS) can determine
the authenticity of large batches of Tamiflu up to 20 times faster
than conventional methods during a presentation Monday at the
American Chemical Society meeting in New Orleans.
"It's a one-step process that doesn't require any extensive
sample preparation," presenter Dr. Facundo M. Fernandez, of the
Georgia Institute of Technology in Atlanta, said in a prepared
statement.
DESI-MS yields sample results in less than one minute. The "gold
standard" for analysis uses high-performance liquid chromatography
(HPLC), a powerful method that can take up to an hour, he said.
"This method is really targeted at screening large amounts of
products" that might be expected during a pandemic of influenza,
Fernandez added. "In case of a crisis, you wouldn't be able to wait
an hour per sample. You'd want to screen hundreds of samples per
day," he said.
When fears of a global epidemic of avian influenza first emerged
in 2005, worried consumers in the United States and other countries
began to horde Tamiflu, seeking prescriptions from physicians and
purchasing the medication from online pharmacies.
In 2007, 86 confirmed human cases of bird flu occurred in the
world, according to the World Health Organization, with 59 cases
resulting in death.
Tamiflu's demand and high cost -- $6.50 a pill -- have made it a
preferred target for fakes, Fernandez noted, and counterfeits have
already surfaced in Chicago, San Francisco and other areas.
"The penalties for counterfeiting pharmaceuticals are much lower
than for trafficking illegal drugs like cocaine," Fernandez said.
"Many of the operations focused on making illegal drugs are
shifting to counterfeiting drugs because of the low penalties and
high profits."
Fernandez tested DESI-MS's effectiveness by collecting different
Tamiflu samples from online pharmacies and found all of them to
contain the active ingredient. However, he warned that customers
who purchase online should use extra caution.
Although some online pharmacies are certified, Fernandez said
people usually look for low prices instead. "What you get online
can be pretty much anything," he said. "It's very easy for the
counterfeiter to bypass the system that's in place to protect the
consumer. And it's very easy for the consumer to get
medications."
More information
The U.S. Department of Health and Human Services has more about
avian
flu.