MONDAY, March 24 (HealthDay News) -- Brooke Zepp, a 63-year-old
South Florida woman, was diagnosed last May with leiomyosarcoma, a
rare cancerous tumor deep inside her abdomen that had wrapped
itself around her aorta and other arteries that supply blood to
vital organs such as the stomach, intestines and spleen.
Surgery wasn't an option, she was told, because there was
literally no room to remove the tumor without damaging those vital
organs. She was given six months to live.
Refusing to give up, Zepp went to the University of
Miami/Jackson Memorial Medical Center, where surgeons at The
Transplant Institute performed what's believed to be the first
operation of its kind: Early this month, they removed six of her
internal organs, freeing up space to cut out the cancer, and then
they reinserted the organs.
Usually, this is an inoperable tumor, Dr. Andreas Tzakis,
director of The Transplant Institute, said during a Monday
teleconference. "In order to remove the tumor, we took a very
unusual approach. We removed all the organs along with the blood
vessels and the tumor," he said.
Before undergoing the operation, Zepp had tried chemotherapy and
radiation, both of which failed. The only option left was surgery,
"but no one wanted to operate," Zepp said during the
teleconference.
"Because people wouldn't operate and I wanted to live, I said,
'Somebody has to do it first,' " Zepp said. "And I wanted to prove
to people, even though many doctors told me not to do this, that I
thought it would be better to take a chance on living than on
dying."
The organs removed during the 15-hour surgery were the stomach,
pancreas, liver, spleen, small intestine and about two-thirds of
the large intestine. Because of their delicate nature, the kidneys
weren't taken out during the procedure, Tzakis noted.
"We had to move very quickly because the organs were removed
from her body and she had no organs in the belly. And we had to
move quickly to cut the tumor out," Tzakis said.
Once the tumor had been removed, Zepp's organs -- which had been
kept chilled -- were placed back in her abdominal cavity and
artificial blood vessels were put in and connected. In total, the
organs were outside her body for about 90 minutes, Tzakis said.
Tzakis said the idea for the surgery was a natural extension of
the work his team had been doing with multiple organ
transplants.
"This is unique and brand-new, but pieces of the surgery were
done before," Tzakis said. "We know how to remove organs -- we know
how to put them in. We've done surgery to remove liver tumors,
taking the liver out of the body, removing the tumor and putting
the liver back in."
The Miami doctors have also performed similar operations
removing tumors from intestines, Tzakis said. "So this came to us
kind of naturally. We've done pieces, we just hadn't done the
entire thing at one time," he added.
Zepp said she feels good. "I feel like I'm coming through a
tunnel and I have a whole life ahead of me," she said.
She added: "I want the rest of the world to know that inoperable
cancers can be operated on. Different cancer centers have different
training and their own vision, and they don't think in the terms
that a transplant surgeon would."
More information
For more on leiomyosarcoma, visit the
American Cancer Society.