TUESDAY, Feb. 12 (HealthDay News) -- Head and neck cancer
patients whose tumors test positive for human papillomavirus (HPV)
tend to survive longer and respond better to treatment than those
who test negative, a new study says.
HPV, a common virus with strains believed to be responsible for
most cervical cancers, has recently been linked to the development
of some head and neck cancers, particularly those of the upper
throat, or oropharynx.
Researchers followed 96 patients in the late stages of cancer of
the oropharynx or larynx (voice box), according to a study
published online Feb. 12 in the
Journal of the National Cancer Institute. All the patients
were enrolled in the same clinical trial and received the same
treatment.
Patients with HPV-positive tumors had higher response rates
after chemoradiation therapy, compared with patients with
HPV-negative tumors (84 percent vs. 57 percent). The two-year
overall survival rates of those with HPV-positive tumors were also
higher (95 percent vs. 62 percent).
"Our data suggest that the risks and benefits of therapies
should be considered separately for HPV-positive and -negative
patients," the authors wrote.
More information
To learn more about head and neck cancers, visit the
National Cancer Institute.
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