Initially, your doctor will ask about your symptoms and medical history, and perform a physical exam.

It is important for you to be open and honest with your doctor about your symptoms and even your sexual history. Your doctor needs this information so that he or she can properly diagnose you and provide you with the treatment that you need. Your doctor will not judge you or your behavior. By understanding your symptoms and your infection, your doctor will be able to prescribe the treatment that is right for you.

Sometimes genital herpes is easy to diagnose because the blisters or open sores around the genital area are easily visible. However, just examining the sores or the rash is not enough. Also, you can have genital herpes even if the sores are not visible.

Lab tests will be done to determine if the herpes simplex virus is in your body. These tests will also be able to tell you if your infection is due to HSV-1 or HSV-2.

There are two types of tests to check for genital herpes.

Viral Culture – If your infection is visible, your doctor will rub a swab (similar to a Q-tip) over an open sore or blister to collect some cells. The cells are then tested to see if the virus is present in those cells. It is recommended that this culture test be taken within the first 48 hours after symptoms appear. The problem with this test is that if your body’s immune system already killed the herpes virus from that sore, the test may come back negative or saying to your doctor that you do not have genital herpes, even if you do. This result is called a false-negative diagnosis.

Blood tests – Your doctor may choose to do a blood test. These blood tests are also called antibody tests because they measure HSV antibodies—the disease-fighting substances in the blood. If the blood tests show HSV antibodies, you are most likely infected with HSV. Newer tests can even distinguish between HSV-1 and HSV-2. It is recommended that you wait at least 12-16 weeks from possible exposure to herpes so that your body has enough time to develop antibodies. This will give you a more accurate blood test.

Specific tests include:

  • Point of Care test (POCkit or biokitHSV-2 Rapid Test) – Right in your physician’s office, your doctor can prick your finger to get a small blood sample. Results are available in less than 10 minutes. This blood test checks for the presence of HSV-2 antibodies.
  • HerpeSelect ELISA – Your doctor will send you to a lab that will draw your blood (from a vein in your arm) for testing for HSV-1 or HSV-2 antibodies. Results are available in approximately 1-2 weeks.
  • HerpeSelect Immunoblot – Your doctor will send you to a lab that will draw your blood (from a vein in your arm) for testing for HSV-1 and HSV-2 antibodies. Results are available in approximately 1-2 weeks.
  • Captiva HSV IgG Type Specific ELISA – Your doctor will send you to a lab that will draw your blood (from a vein in your arm) for testing for HSV-1 and/or HSV-2 antibodies. Results are available in approximately 1-2 weeks.

None of these tests are able to tell you the site of the infection.